Melanoma Epitopes Used in Studying Tumor Regression
Released on = November 14, 2006, 10:31 am
Press Release Author = Debra Thai
Industry = Biotech
Press Release Summary = Melanoma, a malignant tumor that arises in melanocytes, is the most deadly of all skin cancers.
Press Release Body = Although it accounts for only 4% of all skin cancer cases, melanoma is the leading cause of skin cancer deaths1. Several antigens expressed in melanoma cells and recognized by T cells have been identified and used in developing immunization approaches for tumor regression2. These include: MART-1/Melan-A, gp100, Tyrosinase, p15, TRP-1 and beta-catenin2.
AnaSpec, a leading provider of integrated proteomics solutions, offers a broad collection of peptide products for cancer research, including an extensive listing of melanoma immunodominant epitopes and their analogs.
[Ala26]-Melan-A/MART-1 (26-35) Melan-A/MART-1 (27-35) Melan-A, MART 1 (26-35) [Leu27]-Melan-A, MART 1 (26-35) Melan-A/MART-1 (24-34) MELAN-A/MART-1 (32-40) Melanocyte Associated Antigen gp 100 (17-25) Melanocyte Associated Antigen gp100 gp100 (476-485) gp100 (570-579) gp100 (457-466) gp100 (614-622) gp100 (639-647) gp100 (619-627) gp100 (178-187) Tyrosinase (146-156) Tyrosinase (206-214), T9206 [Asp370]-Tyrosinase (368-376) Tyrosinase (1-9) (Asn370) tyrosinase (368-376) Tyrosinase (192-200) Tyrosinase (56-70) Tyrosinase (450-462) Tyrosinase (243-251), core nonamer sequence Tyrosinase (240-251)
For more information visit www.anaspec.com
References: 1. American Cancer Society: Cancer Facts and Figures-2006. Atlanta GA: American Cancer Society, 2006. 2. Rosenberg, SA. J. National Cancer Inst. 88, 1635 (1996).
Web Site = http://www.anaspec.com
Contact Details = 2149 O\'Toole Ave. San Jose, CA 95131 Tel: 800-452-5530 Fax: 408-452-5059 info@anaspec.com www.anaspec.com
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